Last year the DOE Office of Biological and Environmental Research invited an independent group of physicists and engineers (JASON group, run by Mitre Corporation) to review the technology, quality-control, and informatics components of the DOE Human Genome Program. The group released its first advisory report in January. Recommendations emphasize development of advanced technology; improvements in current technology; and establishment of a standardized, quantitative program for data-quality assessment.
A report summary by JASON member Steven Koonin (California Institute of Technology) and commentary were published in the January 2 issue of Science. A response by Phil Green (University of Washington) to specific points in the report was published in the February 20 issue of Science, and a more detailed commentary by Green is available on the Web.
The DOE Human Genome Program recently announced a Request for Applications for instrumentation research to develop substantial evolutionary improvements in current systems and novel revolutionary technologies for efficient genomic analyses.